产品货号：
Z29165
中文名称：
TrkB/NTRK2抗体
英文名称：
Anti-TrkB/NTRK2 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TrkB/NTRK2 antibody |
| 指标别名 | GP145 TrkB;NTRK2;TrkB;TrkB tyrosine kinase |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,Direct ELISA |
| 基因名称 | NTRK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TrkB/NTRK2 recombinant protein (Position:I43-A435). |
| 实际分子量 | 95KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TrkB is also known as NTRK2.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family.This kinase is a membrane-bound receptor that,upon neurotrophin binding,phosphorylates itself and members of the MAPK pathway.Signalling through this kinase leads to cell differentiation.Mutations in this gene have been associated with obesity and mood disorders.Alternative splicing results in multiple transcript variants.Tropomyosin receptor kinase B is the high affinity catalytic receptor for several "neurotrophins",which are small protein growth factors that induce the survival and differentiation of distinct cell populations.The neurotrophins that activate TrkB are:BDNF (Brain Derived Neurotrophic Factor),neurotrophin-4 (NT-4),and neurotrophin-3 (NT-3).As such,TrkB mediates the multiple effects of these neurotrophic factors,which includes neuronal differentiation and survival. |
| Uniprot ID | Q16620 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | neurotrophic tyrosine kinase,receptor,type 2 |
| 蛋白名全称 | BDNF/NT-3 growth factors receptor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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